Téměř kompletní seznam celebrit, jež se v seriálu objevily (včetně hlavních protagonistů):

Dan Castellaneta, Hank Azaria, Nancy Cartwright, Yeardley Smith, Julie Kavner, Harry Shearer, Tress MacNeille, Marcia Wallace, Russi Taylor, Phil Hartman, Joe Mantegna, Frank Welker, Kelsey Grammer, Jon Lovitz, Greg Berg, Albert Brooks, Alex Rocco, Charles Napier, James Earl Jones, George Takei, Pamela Reed, Elizabeth Taylor, Glenn Close, Alec Baldwin, Ron Howard, Eric Idle, Leonard Nimoy, Sam McMurray, Danny DeVito, Adam West, Michael McKean, Sara Gilbert, George Harrison, Michelle Pfeiffer, Patrick Stewart, Paul Winfield, Dave Thomas, Gedde Watanabe, William Daniels, Adam Clayton, Larry Mullen Jr., Bono, Kim Basinger, The Edge, John Kassir, Edward Asner, Lucy Lawless, Stacy Keach, Justin Timberlake, Joey Fatone, Ricky Gervais, Lee Ranaldo, Weird Al Yankovic, Kathleen Turner, Kiefer Sutherland, Paul Newman, Michael Jackson, Maurice LaMarche, Burt Ward, Johnny Cash, Mick Jagger, Lenny Kravitz, Keith Richards, Jane Kaczmarek, J. K. Rowling, Natalie Portman, Julia Louis - Dreyfus, Amy Poehler, Tom Savini, Dustin Hoffman, Louis Freese, Stephen King, Steve Buscemi, George Carlin, Sarah Michelle Gellar, Hugh M. Hefner, Jack White, Meg White, Gary Coleman, Harry Morgan, Matt Groening, Fran Drescher, Alan Moore, Dennis Rodman, Mel Gibson, Kirk Hammett, Lars Ulrich, James Hetfield, Larry Hagman, Frances McDormand, Ben Stiller, Reese Witherspoon, Woody Harrelson, Robert Forster, Meg Ryan, Carmen Electra, Tony Hawk, Stan Lee, Larry King, Penny Marshall, Sting, David Hyde Pierce, Richard Dean Anderson, Buzz Aldrin, Liam Neeson, Mickey Rooney, Bob Denver, Isabella Rossellini, Markéta Irglová, James L. Brooks, Travis Barker, Jodie Foster, Teller , Penn Jillette, Betty White, Simon Cowell, Steven Wright, John Di Maggio, Ernest Borgnine, Jim Jarmusch, John C. Reilly, Drew Carey, James Lipton, Shohreh Aghdashloo, James Caan, Drew Barrymore, Neil Patrick Harris, Mark Hamill, Anne Hathaway, Stephen Hawking, Kathy Griffin, Richard Lewis, Michael York, James Brown, Lily Tomlin, Andrea Martin, Donald Sutherland, Jim Varney, Glen Hansard, Beverly D'Angelo, Johnny Carson, Bette Midler, Luke Perry, Anthony Kiedis, Flea, R. Lee Ermey, Tom Jones, Christina Ricci, Edward Norton, Jerry Springer, Robert Englund, Dolly Parton, Darryl Strawberry, Antonio Fargas, Gary Busey, Elton John, Ray Romano, Jason Bateman, Maria Grazia Cucinotta, Conan O'Brien, Melanie Griffith, Kim Cattrall, Sacha Baron Cohen, J. K. Simmons, Ludacris, Mandy Moore, Emily Blunt, John Waters, Cypress Hill, Brooke Shields, Arnold Schwarzenegger, Ozzie Smith, Steve Sax, Al Gore, Tom Hanks, Ringo Starr, Ken Griffey Jr., Winona Ryder, Denis Franz, Sonic Youth, Steven Spielberg, Anne Bancroft, Ted Danson, Mandy Patinkin, George Wendt, Paul Anka, Susan Sarandon ,Rhea Perlman, Mel Brooks, Kirk Douglas, Bob Newhart, Red Hot Chili Peppers, Jeff Goldblum ,Suzanne Somers, Gilian Anderson, Jack Lemmon, The Smashing Pumpkins, David Duchovny, Martin Sheen, Tom Cruise, Willem Dafoe, Gailard Sartain, Mike Judge, Stephen Jay Gould, Jeneane Garofalo, Jay Leno, Bobcat Goldwaith, Lisa Kudrow, Brendan Fraser, Steven Weber, Fred Willard, Steve Martin, Troy Aikman, Jack LaLanne, Ed Begley Jr., Green Day, Mark McGwire, Tom Arnold, Keone Young, The B-52s, Pat O'Brien, NRBQ, John Goodman, Britney Spears, Don Cheadle, Tim Robbins, Gary Coleman, Clarence Clemons, Shawn Colvin, Randy Bachman, Trevor Denman, Diedrich Bader, Robert Evans, Parker Possey, Jay Mohr, Amy Than, The Who, Leeza Gibbons, Willie Nelson, Jim Forbes, 'N Sync, Andre Agassi, Pete Sampras, Joshua Jackson, Michael Keaton, Venus Williams, Serena Williams, Pierce Brosnan, Frankie Muniz, R.E.M, Delroy Lindo, Richard Gere, Dennis Weaver, Olympia Dukakis, Elliot Gould, Blink-182,Robert Pinsky, Marisa Tomei, Helen Fielding, George Plimpton, Eric Idle, Andy Serkis, Tony Blair, Jennifer Garner, Ian McKellen, Tom Clancy, Mr. T, Mary-Kate Olsen, Ashley Olsen, Jane Leeves, Simon Cowell, Brave Combo, Nick Bakay, Isabel Sanford, Warren Sapp, Michelle Kwan, Tom Brady, 50 Cent, Lucy Liu, LeBron James, William H. Macy, Joe Pantoliano, Metallica, Gore Vidal, Sir Mix-a-Lot, Michael Chabon, Ronaldo, Rudolph Giualianni, Matt Dillon, Lionel Richie, Maya Rudolph, Jack Black, Jon Stewart, Topher Grace, Dixie Chicks, Keith Olbermann, Zooey Deschanel, Lance Armstrong, Mark Cuban, Joe Montana, Jeff Bezos, Merl Reagle, Will Shortz, Fall Out Boy, Neve Campbell, Seth Rogen, Peyton Manning, Mitch Albom, Sarah Silverman, Wren T. Brown, Chris Martin, Bob Costas, Eddie Izzard, Elen DeGeneres, Randy Jackson, Kara DioGuardi ,Bill Clinton,Yael Naim, Angela Bassett, Ryan Seacrest, Philip Rosentahal,George Bush,Magic Johnson,Kenneth Branagh

Studio původně nechtělo úvodní scénu tak brutální, ale režisér Wes Craven si prosadil, že bude naturalistická a krvavá, jinak film nenatočí.
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Cenzoři studia chtěli natočenou úvodní scénu okleštit.Wes Craven ubránil přijatelný kompromis a v sekvenci kdy se kamera blíží k pověšené Casey ubral asi 7 vteřin.
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Drew Barrymore (Casey) měla původně hrát Sidney, ale po přečtení scénáře se rozhodla právě pro roli Casey.
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Drew Barrymore drží i jeden neoficiální primát! Právě za Vřískot z roku 1996. Nikdy předtím v hororovém filmu/thrilleru nezemřela hvězda první velikosti v úvodu filmu.